Decolonizing Psychedelic Research: Frameworks and Practices
Objectives
- Understand the history of bioprospecting and biopiracy in psychedelic plant medicines
- Apply the Nagoya Protocol framework to psychedelic pharmaceutical development
- Distinguish cognitive liberty arguments from indigenous rights arguments
- Evaluate current business models (stewardship, FPIC, reciprocity) against historical patterns
- Understand the entourage effect as a pharmacological expression of indigenous knowledge
Outline
Part 1: The Pattern: Quinine to curare to psilocybin. How bioprospecting works. The María Sabina case in detail.
Part 2: The Legal Frameworks: Nagoya Protocol. FPIC. Native American Church exemptions. The cognitive liberty argument and its limits.
Part 3: Current Business Models: Journey Colab's stewardship model. North Star Ethics Pledge. The Navajo opposition to peyote decriminalization. What "reciprocity" means in practice.
Part 4: The Pharmacological Argument: María Sabina's verdict on synthetic psilocybin. The entourage effect. Why isolated compounds may not capture the full therapeutic picture.
Required reading
- Gregoire, NEO.LIFE (2020)
- Schultes, NIMH Symposium (1967)
- Labate & Cavnar, Therapeutic Use of Ayahuasca (2014)