Unresolved
Psilocybin mushrooms catalyzed the evolution of human consciousness and the doubling of the hominin brain over two million years.
Claim source
Food of the Gods, Chapter 2Current evidence · confidence: low
The neuroplasticity claim is partially confirmed (Shao et al. 2021, dendritic spine growth persisting 1+ month post-exposure). The specific evolutionary timeline lacks fossil or genetic confirmation. No mushroom residue in early hominin coprolites. The mechanism McKenna proposes is unfalsifiable with current tools.Citation
Shao et al. (2021); Nichols, Pharmacological Reviews (2016)