Claim · claimSorter/cs-007
Mystical experience quality predicts therapeutic outcomes better than drug dose alone
Education, not medical advice. Drafts and study material from an independent research library. Citations on this page were checked on Oct 13, 2026; claims in the body text and organizational sources are still under review. What was checked.
Mystical experience quality predicts therapeutic outcomes better than drug dose alone
Partially Confirmed recorded as “Supported by Correlations” LSD: My Problem Child
Reported across several conditions and institutions as a correlation. Barrett & Griffiths (2018): MEQ30 score predicts sustained benefit in depression, AUD, end-of-life anxiety. Gukasyan et al. (2022): MEQ-outcome association persists at 12 months. Whether Phase 3 psilocybin data show the same pattern has not been checked (Source not found; under review). Correlation within trials does not show that the experience causes the benefit; that question is debated.
Barrett & Griffiths (2018); Gukasyan et al. (2022); Viljoen et al. (2025) [Source not found; under review]
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- Source page
- The sources for this item on RN Collins Selected Work
- Long-form
- Hofmann's Sacred Drug Hypothesis: Mystical Experience as Mechanism, the editorial draft this item belongs with
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- See it in the gallery index
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- About this library on RN Collins Selected Work
- Corrections
- Publication rules and the correction form
Course modules that use this claim
- The Science of the Experience Course module
Drafts on the same book
- Ergot and the Pharmacist's Daughter Editorial draft
- The Day the Manufacturer Lost Control Editorial draft
- The Chemist and the Sacred Mushrooms Editorial draft
- One Hundred and Two Years Editorial draft
- The Crystal Structure of the Trip Editorial draft
- The Discoverer's Dilemma: Hofmann, LSD, and the Problem of Intention Editorial draft
- April 19, 1943: What Hofmann Didn't Know He Was Starting Editorial draft
- What the Clinical Record Actually Showed: LSD Therapy 1947-1968 Editorial draft
- Schedule I at Fifty-Five: The Science vs. the Scheduling Editorial draft
- Who Owns the Trip: Psychedelic Patents and the Enclosure Problem Editorial draft
- Cluster Headaches and LSD: The Orphan Indication Editorial draft
- The Hunch That Started Everything Editorial draft
- The Bicycle and the Myth Editorial draft
- What Makes a Problem Child Editorial draft
- Sacred Drug: Hofmann's Most Unfashionable Word Editorial draft
- Hofmann's Sacred Drug Hypothesis: Mystical Experience as Mechanism Editorial draft
- Passage: The Bicycle Ride Editorial draft
- The Basel Years: How a Pharmaceutical Company Handled a Sacred Drug Editorial draft
- The Australian Model: What Happens When a Country Actually Approves Editorial draft
- April 19, 1943 Editorial draft
Reading list for this book
- Reading list: LSD: My Problem Child Reading list
NotebookLM packs on this book
- April 19, 1943 NotebookLM source pack
Bridge pieces that use this book
- María Sabina and the Machine Elves: Two Accounts of Encountering the Other Bridge piece
- The Sacred Drug and the Dominator Drug: Hofmann and McKenna on Alcohol Bridge piece
Science annotations on this book
- A single psychedelic session can produce lasting psychological change persisting for months or years, not... Science annotation
Then vs. Now comparisons on this book
- LSD Potency: The Threshold Claim Then vs. Now comparison
- LSD and Mystical Experience: Hofmann's Claim Then vs. Now comparison
- LSD as Sacred Drug: The 1965 Prohibition Then vs. Now comparison
- Bicycle Day Chemistry: What Hofmann Synthesized Then vs. Now comparison
- LSD and the Law: Hofmann's Hope for Rescheduling Then vs. Now comparison
- LSD in Switzerland 2026: The Country That Never Stopped Then vs. Now comparison
- LSD's Crystal Structure and the Duration Mechanism Then vs. Now comparison
- Cluster Headaches and LSD: The Orphan Indication Hofmann Didn't Know About Then vs. Now comparison
- MDMA and LSD: Hofmann's Two 'Problem Children' Then vs. Now comparison
- The Neuroplasticity Mechanism: What Hofmann Couldn't Have Known Then vs. Now comparison
Other pages in this library that link here
- The First Contacts Course module
- The Suppression Course module
- Psychedelic Science for Science Writers Teaching module