Claim · claimSorter/cs-058
Ibogaine is the most effective single-session treatment for opioid use disorder currently known
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Ibogaine is the most effective single-session treatment for opioid use disorder currently known
Unresolved recorded as “Not Established; Early Uncontrolled Data” Plants of the Gods
Stanford study (Cherian et al., Nature Medicine, 2024, n=30 veterans with traumatic brain injury, open-label with no control group): large improvements in PTSD, depression and anxiety at 1-month follow-up; it did not study opioid use disorder. Observational studies (for example Noller et al., 2018; Davis et al., Journal of Psychedelic Studies, 2017) report reduced opioid use after ibogaine, without control groups. But: no Phase 3 RCT has been completed; cardiac safety (ibogaine prolongs QT interval) requires controlled administration; standard medications for opioid use disorder have strong trial evidence that ibogaine does not yet have. The claim may be true; the evidence base is Phase 2.
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Drafts on the same book
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- How Schultes Found the Mushrooms Editorial draft
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- The Students of Schultes: What the Next Generation Found Editorial draft
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- The Archive and the Fire: Ethnobotany in the Extinction Era Editorial draft
- Who Owns the Pharmacopoeia: Intellectual Property and Sacred Plants Editorial draft
- Peyote Under Pressure: Conservation, Native Rights, and the Psychedelic Industry Editorial draft
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- The Race Against Time: Schultes's Urgency and Hari's Crisis Bridge piece
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- Indigenous Amazonian pharmacological knowledge is accurate enough to have produced every major plant-derived... Science annotation
Then vs. Now comparisons on this book
- Plants of the Gods: Conservation Emergency Then vs. Now comparison
- Ayahuasca Goes Global: Traditional Knowledge Under Pressure Then vs. Now comparison
- Peyote Conservation Crisis Then vs. Now comparison
- Ethnobotany as Urgency: Schultes's Warning Then vs. Now comparison
- The Pharmacological Harvest: What Schultes's Work Has Produced Then vs. Now comparison
- The Psilocybin Pharmacopoeia: From Schultes's 91 Plants to Phase 3 Trials Then vs. Now comparison
- The Schultes Students: Did the Next Generation Continue His Work? Then vs. Now comparison
- Ibogaine's Clinical Translation: Schultes's African Documentation Becoming Treatment Then vs. Now comparison
- The Language Loss Crisis: Schultes's Warning at Acceleration Then vs. Now comparison
- The Peyote Supply Problem: Can Indigenous Ceremony Be Sustained? Then vs. Now comparison
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