Flashcard · flashcards/fc-009
What therapeutic applications have the strongest evidence?
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| Question | Answer | Level |
|---|---|---|
What therapeutic applications have the strongest evidence? therapeutic | (1) Anxiety/depression in terminal illness, psilocybin, strong Phase 2 data (Hopkins, NYU). (2) Treatment-resistant depression, psilocybin, MDMA, Phase 2b/3 data. (3) PTSD, MDMA, MAPS Phase 3 (67% no longer meet diagnostic criteria post-treatment). (4) Alcohol/nicotine addiction, psilocybin, promising pilot data. (5) OCD, psilocybin, small trials. (6) Cluster headaches, patient self-report only, no trial data. MDMA note: MDMA is an entactogen, not a classical psychedelic, different mechanism, different patient population. Nichols (2016); MAPS Phase 3 data; Gregoire, NEO.LIFE (2020) | intermediate |
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