Claim · claimSorter/cs-028

A guided psychedelic session can produce lasting change in personality traits, specifically increases in openness

Education, not medical advice. Drafts and study material from an independent research library. Citations on this page were checked on Oct 13, 2026; claims in the body text and organizational sources are still under review. What was checked.

A guided psychedelic session can produce lasting change in personality traits, specifically increases in openness

Partially Confirmed recorded as “Supported in One Study” Moksha: Letters of Huxley & Osmond

MacLean, Johnson & Griffiths (Journal of Psychopharmacology, 2011): single psilocybin session produced lasting increases in the trait 'openness to experience' (one of the Big Five personality traits), a trait typically stable in adults after age 30. The change persisted at 14-month follow-up. The increase occurred mainly in participants who had a complete mystical-type experience; it is one study of healthy volunteers and needs replication. Consistent with Huxley and Osmond's clinical observations.