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What is the safety profile of classical psychedelics?

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What is the safety profile of classical psychedelics?
safety
No established physiological lethal dose for LSD, psilocybin, DMT, or mescaline. No physical dependence. Rapid tolerance (cross-tolerance between 5-HT2A agonists) prevents consecutive-day use. HPPD (Hallucinogen Persisting Perception Disorder): rare, mechanism unclear, usually mild. NBOMe compounds are NOT classical psychedelics, they are full agonists with cardiovascular toxicity and have caused deaths. Do not conflate.
Nichols (2016); Weil & Rosen (1993) cited in Tupper (2003)
basic