Flashcard · flashcards/fc-001
What is the primary mechanism of action of classical psychedelics?
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| Question | Answer | Level |
|---|---|---|
What is the primary mechanism of action of classical psychedelics? mechanism | Agonist or partial agonist action at serotonin 5-HT2A receptors. This is the consensus mechanism. Glutamate signaling in the prefrontal cortex plays a significant secondary role. Neither serotonin flood nor dopamine, 5-HT2A is the key target. | basic |
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- The First Contacts Course module
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